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REVIEW ARTICLE
Year : 2018  |  Volume : 13  |  Issue : 4  |  Page : 971-975

Role of hypertonic sodium lactate in traumatic brain injury management


1 Department of Neurosurgery, Kanudjoso Djatiwibowo Hospital, Balikpapan, Indonesia
2 Department of Neurosurgery, AW Syahranie Hospital / Faculty of Medicine – Mulawarman University, Samarinda, Indonesia
3 Department of Neurosurgery, Dr. Soetomo General Hospital / Faculty of Medicine – Airlangga University, Surabaya, Indonesia

Correspondence Address:
Dr. Muhammad Reza Arifianto
Galaxy Bumi Permai L1/12B, Surabaya
Indonesia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ajns.AJNS_10_17

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Traumatic brain injury (TBI) following increased intracranial pressure (ICP) is a neuroemergency case which should be managed promptly to prevent secondary brain injury. This will lead to a condition called cerebral energy dysfunction which is an important determinant factor toward worse outcome. Lactate, which was historically known as an end waste product, now is considered as an alternative cerebral energetic fuel. Hypertonic sodium lactate (HSL) is a promising hyperosmolar fluid which serves not only to decrease ICP but also to readily supply exogenous lactate to fulfill increased cerebral energy demand. Pioneer studies have shown the harmlessness and usefulness of HSL in treating pathological condition including TBI.


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