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CASE REPORT
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Primary pleomorphic xanthoastrocytoma of the spinal cord: A case report and review of literature


1 Department of Neurosurgery, Grant Medical College and Sir J.J. Group of Hospitals, Byculla, Mumbai, Maharashtra, India
2 Department of Neuropathology, Grant Medical College and Sir J.J. Group of Hospitals, Byculla, Mumbai, Maharashtra, India

Correspondence Address:
Mayur Sharma,
Department of Neurosurgery, Grant Medical College and Sir J.J. Group of Hospitals, Byculla, Mumbai 400 008, Maharashtra
India
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Source of Support: None, Conflict of Interest: None

Primary pleomorphic xanthoastrocytoma (PXA) of the spinal cord is a rare slow growing tumor. To our knowledge, only five such cases have been reported in the literature till date. We report the clinical, radiological, and histopathological features of a spinal PXA in a 23-year-old female previously operated 5 years back for a spinal tumor, presented with weakness in lower limbs, sphincter incontinence and low back pain. Magnetic resonance imaging scan with contrast reveals an intramedullary lesion in the spinal cord from D8-D10 level. The patient was operated with reexploration of the previous incision, and gross total excision was achieved. Histopathology confirmed the diagnosis of PXA. Clinical and radiological follow-up is required to detect early recurrence. Adjunct radiotherapy or and chemotherapy should be considered only when there is postoperative residual or recurrence, however there are no definite guidelines in view of the rarity of this condition.


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    -  Sharma M
    -  Velho V
    -  Binayake R
    -  Kharosekar H
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