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Diagnosis, treatment, and management strategy of meningioma during pregnancy

1 Department of Neurosurgery, Ankara Atatürk Research and Training Hospital, Ankara, Turkey
2 Department of Neurosurgery, Hitit University Corum Training and Research Hospital, Ankara, Turkey
3 Private Practitioner of Neurosurgery, Liv Hospital, Neurosurgery Clinic, Ankara, Turkey

Correspondence Address:
Ismail Bozkurt,
Department of Neurosurgery, Ankara Ataturk Research and Training Hospital
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Source of Support: None, Conflict of Interest: None

The most common benign tumor of the brain is meningiomas. Usually diagnosed between the ages of 40–60, they are more common in women. Studies have shown a strong relationship between hormones and malignancies. Although meningiomas are slow-growing tumors of the brain, pregnancy seems to induce its growth speed. Studies concerning meningiomas and hormone relationship may explain the reason why symptoms during pregnancy flare. More specifically, the estrogen and progesterone receptor may take an active role through signal transduction in inducing the growth of the tumor. Thus, the dilemma of pregnancy + meningioma arises. In this case, a 21-year-old pregnant with a giant meningioma diagnosed on the symptom of loss of sight is reported. Her pregnancy was terminated, and the tumor was excised. Her vision improved and the histopathological examination showed a progesterone receptor positive meningioma. It is a challenging decision to be made by the physician, the patient and the family when deciding if and when pregnancy should be terminated once an intracranial meningioma is diagnosed.

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