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Phosphaturic mesenchymal tumors involving skull bones: Report of two rare cases

 Department of Histopathology, Bombay Hospital and Medical Research Centre, Mumbai, Maharashtra, India

Correspondence Address:
Toshi Mishra,
Department of Histopathology, Bombay Hospital, 12, Marine Lines, Mumbai - 400 020, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajns.AJNS_176_17

Phosphaturic mesenchymal tumor (PMT) is a rare tumor causing oncogenic osteomalacia (OO). Most such tumors occur in soft tissue and bones of extremities and appendicular skeleton. Intracranial location and involvement of temporal–occipital bone is extremely rare. We report two unusual cases: The first was intracranial, involving the temporal bone, while the other was a skull base tumor arising from the occipital–temporal bone. Both of them presented with paraneoplastic syndrome of OO, resembled a meningioma radiologically, and underwent gross total resection of tumor. Histologically, both of them were diagnosed as PMT, mixed connective tissue variant.

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    -  Mishra T
    -  Desouza MA
    -  Patel K
    -  Mazumdar GA
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