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Year : 2020  |  Volume : 15  |  Issue : 1  |  Page : 194-197

Coexisting moyamoya syndrome and type 1 diabetes mellitus: A case report and review of the literature

1 Division of Neurosurgery, University Surgical Cluster, National University Hospital, Singapore
2 Department of Pediatric Medicine, Division of Pediatric Neurology, National University Hospital, Singapore
3 Division of Neurology, YLL School of Medicine, National University Hospital, National University of Singapore, Singapore

Correspondence Address:
Dr. Nagarjun Bolem
Division of Neurosurgery, National University Hospital, 5 Lower Kent Ridge Road
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajns.AJNS_218_19

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Moyamoya disease (MMD) is an incompletely understood malady that affects many age groups, primarily in a bimodal age distribution. We present a patient with the association of type 1 diabetes mellitus (type 1 DM) and MMD followed by a review of the existing literature. We found five papers that describe this association, in the form of one case report, one case series, and three retrospective reviews. Despite a poor understanding of the underlying pathophysiology, a clear association between autoimmune conditions and MMD appears to exist. Clinicians who manage such patients ought to be vigilant and have a high index of suspicion when young patients with type 1 DM present with new onset of neurological symptoms.

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