An Official publication of The Asian Congress of Neurological Surgeons (AsianCNS)

Search Article
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Advertise Subscribe Contacts Login  Facebook Tweeter
  Users Online: 148 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size  
 
CASE REPORT
Ahead of Print

Primary myoepithelial carcinoma of the clivus: A rare presentation


1 Department of Pathology, Artemis Hospital, Gurgaon, Haryana, India
2 Department of Neurosurgery, Artemis Hospital, Gurgaon, Haryana, India

Correspondence Address:
Shilpi Modi,
H.No. - 104, Tower-2, Malibu Towne, Sector 47, Gurgaon - 122 018, Haryana
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajns.AJNS_144_20

Myoepithelial tumor (MET) of bone is an unusual tumor of uncertain differentiation and histogenesis. Although its presence in various bones has been reported sparsely, the presentation in clivus as primary myoepithelial carcinoma (MEC) has never been reported. They resemble their salivary gland counterparts morphologically and immunohistochemically, but harbor distinct molecular phenotype. At present, moderate nuclear atypia is the acceptable criteria to differentiate MEC from myoepithelioma. Because of their rarity, wide histopathological spectrum, and intraosseous location, MET of bone is easily confused with a variety of primary bone and cartilaginous tumors. Application of immunohistochemistry and, if required, molecular testing are required for making a correct diagnosis. In this article, we describe an extremely rare case of a primary MEC arising from the clivus, which owing to unusual location and immunohistochemical profile was diagnostically challenging.


Print this article
Search
 Back
 
  Search Pubmed for
 
    -  Modi S
    -  Goel D
    -  Goyal P
    -  Gupta A
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed55    
    PDF Downloaded24    

Recommend this journal