Asian Journal of Neurosurgery

CASE REPORT
Year
: 2020  |  Volume : 15  |  Issue : 3  |  Page : 786--793

Rare cases of contrast-induced encephalopathies


Kazutaka Nakao1, Girish Joshi2, Yuichi Hirose3, Riki Tanaka1, Yasuhiro Yamada1, Kyosuke Miyatini1, Binoy Damodar Thavara4, Tsukasa Kawase1, Yoko Kato1 
1 Department of Neurosurgery, Fujita Health University Bantane Hospital, Nagoya, Aichi, Japan
2 Department of Neurosurgery, Fujita Health University Bantane Hospital, Nagoya, Aichi, Japan; Department of Neurosurgery, Apollo Speciality Hospital, Bengaluru, Karnataka, India
3 Department of Neurosurgery, Fujita Health University Bantane Hospital; Department of Neurosurgery, Fujita Health University, Nagoya, Aichi, Japan
4 Department of Neurosurgery, Fujita Health University Bantane Hospital, Nagoya, Aichi, Japan; Department of Neurosurgery, Government Medical College, Thrissur, Kerala, India

Correspondence Address:
Dr. Kazutaka Nakao
Department of Neurosurgery, Fujita Health University Bantane Hospital, Nagoya, Aichi
Japan

Cortical blindness (CB) due to contrast-induced encephalopathy is a rare complication in endovascular procedure. Although exact mechanism is not known, disruption of blood–brain barrier (BBB) by contrast agent is supposed to be caused. We report two cases of contrast-induced encephalopathies after coil embolization of unruptured aneurysm. A 68-year-old woman with unruptured basilar artery aneurysm was treated with endovascular stent-assisted coil embolization. The procedure was successfully accomplished within 172 min using about 160 ml of contrast medium (iopamidol). However, she manifested with CB 3 h after the procedure and seizure on the next day. Immediate computed tomography revealed the cortical enhancement in both occipital lobes. Diffusion-weighted imaging–magnetic resonance imaging and fluid-attenuated inversion recovery sequence 1 day after the procedure revealed edema in both occipital lobes with no findings of ischemia or hyperperfusion. Electroencephalography showed sharp and slow waves in both occipital lobes. She required endotracheal intubation on day 2 to maintain airways and breathing. Her sensorium improved 4 days after the procedure with administration of steroid and anticonvulsant. She was extubated on day 4 after the procedure. She was discharged with persisting CB as a sequel.


How to cite this article:
Nakao K, Joshi G, Hirose Y, Tanaka R, Yamada Y, Miyatini K, Thavara BD, Kawase T, Kato Y. Rare cases of contrast-induced encephalopathies.Asian J Neurosurg 2020;15:786-793


How to cite this URL:
Nakao K, Joshi G, Hirose Y, Tanaka R, Yamada Y, Miyatini K, Thavara BD, Kawase T, Kato Y. Rare cases of contrast-induced encephalopathies. Asian J Neurosurg [serial online] 2020 [cited 2021 Jan 21 ];15:786-793
Available from: https://www.asianjns.org/article.asp?issn=1793-5482;year=2020;volume=15;issue=3;spage=786;epage=793;aulast=Nakao;type=0